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(juired operative advantages over those who re- mained at iiome, by making cnter]>rising journeys to the East Indian Fountain Head of Intracapsulology, and have ac(|uired tirst hand knowledge on this sub- iect, fortified by cx])erimeiilal operating on several hundred Brand Cialis Buy Online unfurtunate blind East Indians, seem to have at least temporarily, regarded this operation as the only one to perform. But it has been observed liiat those enthusiastic returning cataract pilgrims have mostly — one by one — begun by making various modirn-ations of the Smith operation and its special instruments, and eiidetl by using this operation only in "selected cases" — whatever that may mean. I .suspect, however, it means that having once left the "Mysterious East," the personal magnetism of Smith and the fascinations of his surroundings, and once more returned to the conmionplaceness of \mcrica, the in.sjiiration of the master has faded gradually away. They have, 1 fancy, learned f|uite Brand Cialis Buy Online early that this is an operation reijuiring constant ex- perience, and that, whereas in India the supply of i-ataracts is more than ec|ual to the demand, in .\merica even a busy ophthalmologist may not operate on more than fifty senile cataracts a year. 1 think, we might be better occujiicd in perfecting the ijuiti' satisfactory operation with which we are .'dready familiar, and in reaching out along more conser\ative lines for the future intracapsular oper- ation than in doing an experimental, difiicult surgi- cal procedure sim])ly because Smith and a few of his followers do it or because some men are doing it in this country. 7 Wfst MvnisoN Strf.kt. THE ORGANISM CAUSING POLIOMYELI- TIS, AND HOW THE DISEASE PROB- ABLY SPREADS. I'.v HokACE Greeley, M. D., Brooklyn, N. Y. Many early investigators into the cause of epi- demic infantile paralysis reported having found organisms Brand Cialis Buy Online varying in form from cocci to bacilli in the nerve centre lesions, and various experiments were conducted to determine the relationship of the bacteria isolated to the disease. Most prominent, in recent years in this country, was the work of I'^lexner and Noguchi, in which "glol)oid bodies" were cultivated in the serum-fresh tissue media said to Brand Cialis Buy Online have been first employed in bacteriology by TaroEzi. By this method the surface of the media in the culture tube was covered with a layer of lirjuid paraffine with the object Brand Cialis Buy Online of ex- cluding the oxygen of the atmosphere from access to the medium. Wolf has shown {^Lancet, 1917, page ~^j) that the licjuid paraffine layer has a greater aflinity for atmospheric oxygen than the culture media and therefore it could not act as sup>- ])Osed. As is well known these experimenters re- produced the disease in monkeys by the inoculation of such cultures. Others had reported a like rcpro- iluction of the malady. Rosenow and others grew the organism in a coccus form, on ordinary nutrient agar to which a little fresh blood had been added before congelation, and likewise reproduced the malady. Rosenow's earlier publications inferred that he regarded the disease as produced by an ordinary streptococcus which, like the cocci, he seems to have proved cause various forms of arthritis ; he supposed they had developed special affinity for the nerve centres. Apparently it was with tiiis understanding that a series of experiments were done last year in the Rockefeller Institute to prove that ordinary strepto- cocci could not be the cause of poliomyelitis. During the ejiidemic in this city, in i(>i6, Brand Cialis Buy Online the au- thor carried out some bacteriological and serological work, the results of which, although published ex- Brand Cialis Buy Online tensively at the time, have recently become of par- ticular interest since they have been confirmed by Doctor Rosenow and Dr. L. D. Bristol, the latter working witii cultures obtained from the Rockefeller Institute. The net result of the author's experiments were that, working with cultures taken from the spinal cords and brains of victims of the 1916 outbreak, he isolated in pure cultures Brand Cialis Buy Online a bacillus which could be grown both under the "globoitl body" form of the Rockefeller Institute and the coccus form of Doctor Rosenow. i\irthermore, two cultures in coccus form supplied by Doctor Rosenow at the time, to the author, were developed into the bacillus form. The characteristics of the poliomyelitis bacillus as described by the author are briefly as follows : I-'ont'. and cuUivcition. — If cultures, in media con- sisting entirely or mainly of Brand Cialis Buy Online serum, be made from ;he infected nerve centres of cases of poliomyelitis, the organisms will develop as "globoid" or coccoid in form, and many of the individuals will lie very minute 926 GREELEY: POLIOMYELITIS. [New York Medical Joukna Cultures, either direct from pathologic material or replants of '"globoid" or coccoid cultures, in fluid media in which the serum content was small (the media employed was mainly bouillon containing ten per cent, limcwater) or on solidified Loefller's medium Brand Cialis Buy Online (such as is used for diphtheria bacilli) Fig. I. — Poliomyelitis bacillus, globoid body form. Magnification 1500. flushed with the limewater Brand Cialis Buy Online bouillon, developed bacillus forms. These bacillus forms could,be grown as small Gram negative rods or, by care in fostering particularly vigorous growth (see original paper) be developed into large bipolarly Gram positive bacilli.