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[New York Medicai, Journal. were discontinued, the patient leaving the hospital weak, but in good mental condition. It was then for the first time that I obtained an intelligent con- nected history from her. Two years after the opera- tion she was in good physical and mental condition. I quote from the nurse's notes : November 4, 1914. Second dose of vaccine, 75,000,000. Slight rise of temperature, marked rapidity of pulse, ex- treme restlessness, and slight delirium, lasting twelve hours. Doctor's notes on November i6th, the beginning of the si,\th week after the operation. Marked improvement in the general condition and spirit; noises in the ears still present; crash of paper causes agony; can read the dial on the watch for the first time today. Nurse's note on November 20th, after the si.xth dose of Cheap Non Prescription Cialis the vaccine : Difficult breathing; immediate weakening of the pulse. One hour after, pulse hardly perceptible, responded to stimulation slightly; weak and exhausted condition; lasted twelve hours. Urinalysis : albumin diminished, indican still in large quantity. December 2d. Ninth Cheap Non Prescription Cialis dose of the vaccine, 100,000000: reaction very slight, general condition improved. Urine, no albumin, moderate amount of indican. Apparently the colon vaccine saved her life. Conclusions. The predominating factor in the symptomatology of chronic intestinal toxemia is the colon bacillus. In diseased conditions of the colon, the colon bacillus may become very hannful to the human organism by forming and liberating toxins, thus causing a toxemia. This toxemia gives a definite symptomatology called chronic intestinal toxemia. Putrefactive organisms often play an important part in intestinal toxemia, but the lasting effects are Cheap Non Prescription Cialis due to the colon bacillus. In the study and treatment of all long standing or severe chronic intestinal toxemias, autogenous colon vaccines should be administered in proper doses. Autogenous colon vaccines Cheap Non Prescription Cialis are helpful in the diag- nosis of chronic intestinal toxemia. The method of action of the colon bacillus vac- cine is probably an immunization and sensitization of the body cells. REFERENCES. I. G. R. SATTERLEE: New York Medical Journal, June 12, 1915. CI. No. 24. 2. H. CONRADI and O. KURPJIUVEIT: Munchen tvcdi::inische Wochcnschrift, 1905. lii, 1762: ibid., 1005. lii, 21(5. 3. VICTOR C VAUGHAN, JR.: Journal A. M. A.. April 29, 1905. 4, JOHN B, DEAVEK: Afpeniicitis . Diagnosis and Treat- rncnt, [Q05 5- J- G. ADAMI: Colorado Medical Journal, Denver, 1014 xi. 34 to 49. 6. J. W. DRAPER: Journal A. M. A.. Septemlier 26. 1914. 7. F. T. MURPHY and B BROOKS: Archives of Inter- nal Medicine. 19 15. xv, 39,1. 8. NOBLE P. BARNES: Transactions of the American Therapeutic Society. 1917, p. 134, 9. G. R. SAT- TERLEE: AmcricoH Journal of Medical Sciences, November, 1916, V, CI. iii. 727. 125 West Fifty-eighth Street. The Surgical Treatment of Pernicious Anemia. — C. K. P. Henry (The Canadian Medical Associa- tion Journal, February, 1918) from a review of the literature and personal experience concludes that this disease continues to be uniformly fatal, but that the life of the patient is prolonged by splenectomy and transfusion. After splenectomy, when the case is clinically greatly improved the Cheap Non Prescription Cialis blood picture still is tluit of typical pernicious anemia. The splenec- tomy is always best preceded by transfusion. SOME ASPECTS OF SYMPTOMATIC TREATMENT.* By Edward E. Cornwall, M. D., F. A. C. P., New York. In that not very remote period of medicine before vaccines and serums and internal secretions and metabolism became therapeutic catch words, a period which we sometimes allude to as the prescientific period, treatment was generally described as of three kinds, specific, Cheap Non Prescription Cialis expectant and symptomatic. The specifics in those days were verj' few, and expectant treatment was unpopular ; symptomatic treatment occupied most of Cheap Non Prescription Cialis the field. Even now, when Cheap Non Prescription Cialis true specifics, mostly biological, are constantly being dis- covered, symptomatic treatment Cheap Non Prescription Cialis constitutes a very large part of medical practice. But increase in our scientific knowledge, particularly in our knowledge of physiology, brings up certain questions in connec- Cheap Non Prescription Cialis tion with symptomatic medicine. One is : What is a symptom, and to what extent is symptomatic treatment rational or permissible? We may define a symptom as an unusual function- ing of the body, or, to use more precise terminology, as functioning which is abnormal, hypernormal or hvponormal. Unusual functionings are more or less regularly associated with disease conditions, and also occur without demonstrable pathological basis. Symptomatic treatment, as a universal dogma, rests on the assumption that these unusual function- ings are themselves morbid manifestations, or a part of the disease, and as such deserve to be suppressed or abated. Acting on this assumption, fever has regularly been reduced as a bad thing, diarrhea has been checked, constipation has been overcome, pain